MYOM2 and AL amyloidosis: The detection of monoclonal κ or λ immunoglobulin light chain deposition in extracellular tissues[28,29] should alert clinicians to neoplastic diseases, such as multiple myeloma.[30] In multiple myeloma, amyloidosis due to λ light chains is more common than that due to κ light chains.[4] Both primary and secondary AL are associated with multiple myeloma, yet they exhibit significant differences in clinical prognosis.[31] Early methods of immunoelectrophoresis and immunofixation were not sensitive enough to detect M protein.