KLF17 and neoplasm: However, our results appear to contrast with a study by Feng et al. (2021), which reported that hyperthermia-induced miR-409-3p overexpression suppressed GC metastasis by targeting KLF17.[4] This apparent paradox may reflect context-dependent roles of miR-409-3p, where its tumor-suppressive effects are hijacked by oncogenic ceRNA networks in advanced GC.