VEGFA and Pulmonary Infarction: Methylprednisolone can inhibit the expression of vascular endothelial growth factor, thereby reduce vascular permeability and stabilize the tight junctions of the capillary endothelium, leading to a reduction in red blood cell exudation.[12–14] Additionally, methylprednisolone can inhibit inflammatory exudation, resulting in a reduction in the range of pulmonary consolidation on CT images, but it cannot reverse the necrotic core of pulmonary infarction.[15,16] This further explains the reexpansion of the lesion on CT images after drug withdrawal.