Fig. 8F reveals upregulated signaling in T1D through proteins and pathways linked to inflammation, immune modulation, and ECM remodeling, including GAP, VTN, TGFb, EGF, SPP1, PDGF, LAMININ, and COLLAGEN, suggesting structural changes and adaptive responses to tissue damage. The gene discussed is VTN; the disease is type 1 diabetes mellitus.