Furthermore, it has been found that mesenteric lymph node B cells (MLB) migrate to the intestine in 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced colitis through the C–C Chemokine Receptor 8—C–C Chemokine Ligand 1 (CCR8-CCL1)axis and exacerbate the inflammatory response by modulating T cells [50]. This evidence concerns the gene CCR8 and colitis.