PLAUR and cancer: Emerging candidates for senolytic strategies for precancer interception include the BCL-2 family inhibitor Navitoclax to inhibit autophagy,332 dasatinib combined with quercetin for targeting RTKs and the PI3K/mTOR pathways,333,334 and CAR-T cells which target urokinase plasminogen activator receptor (uPAR) on the surface of senescent cells,335 have shown promise in cancer and other disease models.