NLRP3 and Parkinson disease: In the category Cellular Component (CC) (Fig 4), significant terms involve “NLRP3 inflammasome complex”, “Caspase complex,” “Extracellular region,” and “Extracellular space.” These components are associated with key inflammatory processes, particularly the NLRP3 inflammasome, which has been implicated in the neuroinflammatory cascades contributing to dopaminergic neuronal death in PD.