ESR2 and endometriosis: Xue et al. presented that BPA stimulates the development of endometriosis by damaging the balance between ERα and ERβ and thus stimulates the expression of ERβ pro-proliferative abilities, via targeting GPER1/Phosphoinositide 3-kinase (PI3K)/ mammalian target of rapamycin kinase (mTOR) and WD repeat-containing protein 5 (WDR5)/ Tet methylcytosine dioxygenase 2 (TET2) pathways [112].