The identification of key hub genes, such as EGFR, FOS, and PTGS2, suggests that PFAS may contribute to the pathogenesis of endometriosis by disrupting hormone receptor signaling (e.g., nuclear receptor activity), activating oxidative stress responses (e.g., NADPH oxidase activity), and promoting abnormal epithelial cell proliferation. The gene discussed is EGFR; the disease is endometriosis.