Immune dysregulation/inflammatory signaling: IL1R2 (decoy receptor dampening IL‐1 responses), LTB (lymphotoxin‐β), PRKCA and MARCO (pattern recognition on activated myeloid cells), and SLC11A1, RNF10, and COMMD6 (NF‐κB modulation) indicate perturbed inflammatory control and impaired effector coordination characteristic of sepsis immunoparalysis [36, 37]. Here, COMMD6 is linked to Sepsis.