Patients with PSVD had the following associated conditions: cystic fibrosis (n = 3), HIV infection (n = 2), TERT gene mutation (n = 1), heterozygous prothrombin gene mutation (n = 1), antiphospholipid syndrome associated with protein S deficiency (n = 1), Sjögren’s syndrome and hypogammaglobulinemia (n = 1), systemic lupus erythematosus (n = 1), common variable immunodeficiency (CVID) (n = 1), and none (n = 1). Here, F2 is linked to HIV infectious disease.