To determine the relationship between MUC4 mutation/down‐regulation and TEs, we constructed a lower limb DVT model by ligating the unilateral iliac vein (Figure S3A) and compared the incidence of thrombosis and thrombus length among the WT, Muc4‐KO, Piga‐KO and Piga/Muc4‐DKO groups after surgery. The gene discussed is PIGA; the disease is deep vein thrombosis.