CDK12 and myeloproliferative neoplasm: Elevated CDK13 expression has been reported in myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T), in which 80–90% of patients harbor SF3B1 mutations, a splicing factor regulated by CDK12/13 [82–84].