PTEN and neoplasm: The current literature provides only one instance that explores BGLT3 as a tumor suppressor in TC, namely the study by Zhao et al. In addition to demonstrating the repressive effect of c-MYC on the BGLT3 promoter, they observed a pronounced attenuation of cellular proliferation, growth, and migration of PTC cells in which they restored BGLT3 expression, attributing these effects to the increased stability of PTEN.