LMNA and Hutchinson-Gilford progeria syndrome: Thirteen pathways were significantly affected in GFP-progerin expressing cells only, including the inflammatory response, KRAS and p53 signaling, G2/M checkpoint, and adipogenesis (Table 4, green; Table S3), whereas seven pathways were significantly misregulated only in HGPS patients, including Notch signaling and Wnt/β-catenin signaling (Table 4, red; Table S3).