To further explore potential mechanisms underlying long‐term cognitive impairment in patients with anti‐NMDAR encephalitis, we assessed hippocampal neurogenesis, as previous studies have shown that CHI3L1 can impair neural stem cell (NSC) differentiation through CRTH2‐mediated suppression of β‐catenin signaling [19, 28]. The gene discussed is CHI3L1; the disease is Cognitive impairment.