C1R and neoplasm: Similarly, in the NCG mouse tumor model, immunohistochemical analysis of the ShC1R group compared to the control group showed decreased C1R (***p < 0.001) expression, elevated expression of the epithelial marker E‐cadherin (*p < 0.05), and reduced expression of the mesenchymal markers N‐cadherin (**p < 0.01) and Vimentin (*p < 0.05) (Figure 6J,K).