Simple linear regression of the same 5 myokines (CXCL9, CXCL10, IL-6, IL-15, and IL-18) in IFNβ-treated myobundles to JDM patients revealed a positive association, yet not statistically significant in both media and sera correlation (Y = 0.6048*X + 1.265, padj=0.17, R2 = 0.52, 95% confidence interval for slope ranged from -0.4719 to 1.682) and gene transcription in myobundles and muscle (Y = 0.4220*X + 0.3491, padj=0.16, R2 = 0.53, 95% confidence interval for slope ranged from -0.3017 to 1.146) (Figure 7B). The gene discussed is IL18; the disease is juvenile dermatomyositis.