FAM225A and myasthenia gravis: We found that the expression of Th2-related transcription factors (GATA3) was significantly increased and the Th1/Th2 ratio decreased in the OE-FAM225A group, indicating FAM225A mainly affected Th2 cell differentiation and the imbalance of Th1/Th2, which might provide new insights into the study of the immune mechanism of triple-SN MG; however, further systematic experimental verification is required.