While the presence of Lcn2 in allograft biopsies correlates with the severity of AKI post-transplantation (22), there is limited data on the biological functions and metabolism of endogenously synthesized Lcn2 in kidney allografts, as well as the effects of exogenously administered recombinant Lcn2:Siderophore: Fe complex (rLcn2) in recipients. This evidence concerns the gene LCN2 and acute kidney injury.