ALDH1A1 and posterior cortical atrophy: Specifically, GLS1 inhibitors can significantly enhance the radiosensitivity of PCa cells (187); high expression of ALDH1A1 is closely associated with bone metastasis of PCa and post-radiotherapy recurrence risk (190); meanwhile, CAF-related gene signatures have high predictive efficacy for post-radiotherapy biochemical recurrence and distant metastasis (188).