MPO and Cirrhosis: Translational studies of cirrhosis report higher circulating levels of trap markers, including histone H3 citrullinated-DNA (H3Cit-DNA) and myeloperoxidase (MPO)-DNA complexes (37), alongside reduced phagocytic and killing abilities (99), disturbed control of oxidative bursts (100), increased tissue infiltration with poor effector killing, and abnormal apoptosis (101).