The PWAS identified 7 genes (MMP12, F11, ENGASE, SH3BGRL3, SPATA20, SWAP70, SCARA5) whose cis-regulated plasma protein levels were associated with stroke and its subtypes at a FDR of P < 0.05 (Table 1, Fig. 2 and Table S2). The gene discussed is MMP12; the disease is stroke disorder.