PROS1 and thrombophilia: In December 2022, comprehensive thrombophilia genetic testing—including full gene sequencing and deletion/duplication analysis of 11 genes (ADAMTS13,F2,F5,F9,FGB,FGG,MPL,PROC,PROS1,SERPINC1,THBD)—identified a heterozygous pathogenic variant in theF2gene (NM_000506.3): Prothrombin Belgrade (c.1787G > A, p.Arg596Gln).