It has been reported that nearly 50% of orthopedic patients suffer from malnutrition before surgery (Pruzansky et al., 2014; Golladay et al., 2016), so we assessed whether malnutrition-evaluating markers (PLT, WBC count, LCT, HGB, albumin, and PNI) (Kurtz et al., 2018; Maimaiti et al., 2021) can predict the failure of PRABCSI in PJI treatment. The gene discussed is CYGB; the disease is nutritional deficiency disease.