GNA15 may play a role in CRC through affecting the growth of cell lines such as HCC56, DLD1 and biological processes such as antigen-antibody binding, immunoglobulin complex, phagocytosis, antigen processing and presentation, cell adhesion molecules, Th17 cell differentiation, and toll-like receptor signaling pathway. The gene discussed is GNA15; the disease is colorectal carcinoma.