SLC22A12 and hyperuricemia: Some single herbs can affect uric acid excretion by regulating the expression of transporters: Fraxinus rhynchophylla can reduce the serum uric acid of hyperuricemic rats by inhibiting two uric acid reabsorption proteins, URAT1 and GLUT9, and can also alleviate kidney damage caused by hyperuricemia and reduce urinary creatinine level.