Classic compound prescriptions and improved prescriptions are widely used in clinical practice: Simiao Wan, composed of Phellodendron chinense, Atractylodes lancea, Achyranthes bidentata, and Coix lacryma-jobi, has been used for the treatment of gout and gouty arthritis for more than 700 years; The modified Jiawei Simiao Wan based on Simiao Wan can play a role in lowering uric acid by inhibiting XOD activity and regulating the expressions of URAT1 and OAT1 (63). The gene discussed is SLC22A12; the disease is gout.