Afshinnia and Pennathur (28) found that the incidence of osteoporosis in the femoral neck in patients with hypoalbuminemia was significantly higher than that in those with normal albumin, and the difference was statistically significant; therefore, hypoalbuminemia should be actively corrected to reduce the occurrence of related osteoporosis, reduce muscle strength reduction, and prevent the occurrence of osteoporotic fractures the same time. This evidence concerns the gene ALB and Hypoalbuminemia.