Exosomes derived from MSCs can not only induce autophagy in glomerular endothelial cells through the mammalian target of rapamycin (mTOR) signaling pathway to improve DN (69), but also inhibit pyroptosis in proximal tubular cells of the kidney through miR-30e-5p (70), which is the first time the role of exosomes in inhibiting cell pyroptosis in T2DM has been reported. This evidence concerns the gene MTOR and type 2 diabetes mellitus.