Another study shows that the inhibitory agents derived from human placental mesenchymal stem cells (hPMSCs) from patients with gestational diabetes mellitus (GDM) can promote the proliferation and angiogenesis of ECs by targeting intercellular cell adhesion molecule-1 (ICAM-1) through miRNA-130b-3p and increase the expression of angiogenesis-related factors (34). Here, ICAM1 is linked to gestational diabetes.