Natural exosomes-like nanoparticles in mung bean (MELN) sprouts can alleviate the progression of T2DM by activating the phosphatidylinositol 3-kinase (PI3K)/Akt/glucose transporter type 4 (GLUT4)/glycogen synthase kinase-3β (GSK-3β) signaling pathway, which reduces fasting blood glucose levels, triglycerides (TG), total cholesterol (TC) and reduces the inflammatory infiltration and oxidative stress levels in liver cells, thereby improving the survival ability of liver cells (55). The gene discussed is AKT1; the disease is type 2 diabetes mellitus.