Moreover, individuals with elevated Lp(a) concentrations (≥50 mg/dL) and high coronary artery calcium (CAC) scores (≥100 Agatston units) had a markedly greater 10-year ASCVD incidence compared with those with low Lp(a) and zero CAC (adjusted HR: 4.71; 95% CI: 3.01 to 7.40). Here, LPA is linked to atherosclerosis.