Combining Gal-3 with NT-proBNP and high-sensitivity troponin T (hs-TnT), for example, offers superior discrimination for predicting death or HF hospitalization post-AMI compared to any single marker or traditional risk factors (Idzikowska et al., 2022; O'Donoghue et al., 2016). The gene discussed is LGALS3; the disease is hydrops fetalis.