While CysLTR2 is generally considered to have a more prominent role in the cardiovascular system due to its high expression in the heart (Heise et al., 2000; Takasaki et al., 2000), it is increasingly recognized that both CysLTR1 and CysLTR2 play important but distinct roles in cardiovascular diseases (Colazzo et al., 2017). The gene discussed is CYSLTR2; the disease is cardiovascular disorder.