While CysLTR2 is generally considered to have a more prominent role in the cardiovascular system due to its high expression in the heart (Heise et al., 2000; Takasaki et al., 2000), it is increasingly recognized that both CysLTR1 and CysLTR2 play important but distinct roles in cardiovascular diseases (Colazzo et al., 2017). This evidence concerns the gene CYSLTR1 and cardiovascular disorder.