Alzheimer’s disease (AD) is the most common neurodegenerative disorder, marked by the progressive accumulation of amyloid-β (Aβ) plaques, neurofibrillary tangles composed of hyperphosphorylated tau, and chronic neuroinflammation (Serrano-Pozo et al., 2011; Hampel et al., 2021). This evidence concerns the gene MAPT and Alzheimer disease.