CSF, cerebrospinal fluid; NPSLE, neuropsychiatric systemic lupus erythematosus; SLE, systemic lupus erythematosus; pSS, primary Sjögren’s syndrome; NMOSD, neuromyelitis optica spectrum disorder; RA, rheumatoid arthritis; NOS, Newcastle-Ottawa Scale; JBI, Joanna Briggs Institute; AQP4, aquaporin-4; CCP, cyclic citrullinated peptide. The gene discussed is AQP4; the disease is peeling skin syndrome.