ERBB2 and invasive breast carcinoma: Core biopsy confirmed invasive breast carcinoma (ER+, HER2+, cErB2 overexpression). Staging CT (thoraco-abdominal-pelvic) revealed extensive multinodular hepatic metastasis, consistent with stage cT4N+M1 (American Joint Committee on Cancer (AJCC) 7th edition) (Figure 1).