PTCH1 and xeroderma pigmentosum: The occurrence of BCC is associated with genetic factors, with certain genetic disorders such as Gorlin syndrome, xeroderma pigmentosum, and ocular albinism increasing the risk of developing BCC (16–21).Abnormalities in the PTCH gene, which controls cell proliferation and differentiation, may be associated with the development of BCC (22, 23).