After that, to obtain more accurate MRGs characteristics, we screened 9 prognosis-related DEGs (JUP, CAT, TRIP13, ACAD11, SYNE2, IGF2BP2, SLC25A25, CDC20, NDRG1) related to the prognosis of ccRCC by univariate Cox regression analysis. The gene discussed is IGF2BP2; the disease is nonpapillary renal cell carcinoma.