After that, to obtain more accurate MRGs characteristics, we screened 9 prognosis-related DEGs (JUP, CAT, TRIP13, ACAD11, SYNE2, IGF2BP2, SLC25A25, CDC20, NDRG1) related to the prognosis of ccRCC by univariate Cox regression analysis. Here, SLC25A25 is linked to nonpapillary renal cell carcinoma.