MiR-873-5p and miR-526a2 (sequence identity with miR-518d-5p) were included in the study because of their relevance to liver diseases: miR-873-5p is found to be upregulated in liver tissues of MASLD patients, an important target of miR-873-5p being the mitochondrial glycine-N-methyltransferase, thus affecting the methionine cycle and the activity of the electron transport chain.23 This evidence concerns the gene GNMT and metabolic dysfunction-associated steatotic liver disease.