In bladder urothelial carcinoma and THCA, the AR/ERα ratio showed modest effects associated with worse survival (HR = 1.12; 95% CI, 1.02–1.23; P = 0.018 and HR = 1.11; 95% CI, 1.01–1.23; P = 0.027, respectively). The gene discussed is ESR1; the disease is bladder transitional cell carcinoma.