DNM1L and glioblastoma: In glioblastoma, BCL2L13 is upregulated, and BCL2L13 overexpression promotes mitophagy.141 Mitochondrial fission may play a role in this process, as deficiency of BCL2L13 leads to reduced phosphorylation of DRP1 at Ser616, but not Ser637, corresponding to decreased DRP1 activity.