In the human CRC cell line DLD1, TAT-APC11 selectively increased STAT1 phosphorylation and expression of IRF1 and MHC-I components (HLA-A, HLA-B, HLA-C, and B2M), whereas TAT-APC11M exhibited no effect (Fig. 6m, n). The gene discussed is HLA-B; the disease is colorectal carcinoma.