When we examined key pro- and anti-ferroptotic molecules at the protein level, we detected significantly increased expression of ferritin heavy chain 1 (FTH1), ferritin light chain 1 (FTL1), divalent metal transporter 1 (DMT1), and glutamate-cysteine ligase catalytic subunit (GCLC) in primary CLL cells compared with healthy B cells (Fig. 1f, Supplementary Fig. 1k). This evidence concerns the gene SLC11A2 and B-cell chronic lymphocytic leukemia.