TJP1 and Patent ductus arteriosus: The results showed that, in terms of intestinal barrier function, compared to the Model group, the relative mRNA expression levels of Occludin and Zonula Occludens-1 (ZO-1) in the colon tissues of PDA@MPD and En.-MPD group mice were upregulated (Fig. 7A-B), and the protein expression levels of Occludin also showed an upward trend (Fig. 8A-B).