ADRB2 and colorectal adenocarcinoma: In colorectal adenocarcinoma, high β2AR expression was associated with worse prognosis, with poor disease‐free (HR 3.17; 95% CI 2.29–9.68; p < 0.01) and overall survival (HR 2.27; 95% CI 1.51–3.72; p < 0.01), as well as increased tumour aggressiveness, cell proliferation and metastasis in a cohort of 147 patients in Japan who underwent surgical resection [8].