Meanwhile, Astragali Radix has demonstrated antithrombotic effects in both deep vein thrombosis and tail thrombosis models [30, 31], and its principal component, Astragaloside IV, targets signaling pathways such as PI3K/Akt and Ca2+ influx [32, 33], which are central to thrombus formation. Here, AKT1 is linked to deep vein thrombosis.