The qRT-PCR results confirmed that TREM2 deficiency increased the levels of Cxcl10 (T1D vs. T1D + TREM2 cKO: p = 0.0307, Fig. 8g) and decreased the levels of Ccr5 (T1D vs. T1D + TREM2 cKO: p = 0.0065, Fig. 8g) and Cx3cr1 (T1D vs. T1D + TREM2 cKO: p = 0.0030, Fig. 8g). This evidence concerns the gene CCR5 and type 1 diabetes mellitus.