In triple-negative basal-like breast cancer, elevated expression of the glutamine transporters alanine-serine-cysteine transporter 2 (ASCT2) and sodium-coupled neutral amino acid transporter 2 (SNAT2) promotes glutamine uptake dependency, with subsequent regulation of cancer cell growth through the mTORC1 signaling pathway.166,167. The gene discussed is SLC1A5; the disease is breast cancer.