APOB and coronary artery disorder: When feasible, ApoB (> 130 mg/dL), lipoprotein(a) (> 125 mmol/L) and hs-CRP (≥ 2 mg/L) measurement in addition to premature family history provide justification for statin therapy, and imaging of subclinical CAD with computed tomography angiography or CAC scoring may help resolve uncertainty.