AF, atrial fibrillation; ApoB, apolipoprotein B; ASCVD, atherosclerotic cardiovascular disease; BID, twice daily; CABG, coronary artery bypass grafting; CAD, coronary artery disease; CHD, coronary heart disease; CTA, computed tomography angiography; CVD, cardiovascular disease; DM, diabetes mellitus; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; FCS, familial chylomicronemia syndrome; HDL-C, high-density lipoprotein cholesterol; HTG, hypertriglyceridemia. The gene discussed is APOB; the disease is coronary artery disorder.