Our m5C meRIP‐qPCR assay in CRC cells did not find evident m5C enrichment on TROP2 mRNA (Figure S9A) compared to positive control68 and modulating YBX1 did not significantly affect TROP2 mRNA stability (Figure S9B), which further strengthens our findings. This evidence concerns the gene TACSTD2 and colorectal carcinoma.