TACSTD2 and colorectal carcinoma: To investigate the in vivo effect of TROP2 expression, we established TROP2 positive (+) and negative (‐) xenograft models using control and TROP2‐OE Lovo cells in immunodeficient mice and then re‐isolated CRC cells for UPLC/MS analysis (Figures 2C and D and S3B and C).