HDAC9 and cancer: Amongall modifications analyzed, H3K18ac exhibited the most pronounceddecline, suggesting its preferential sensitivity toward arsenite.H3 hypoacetylation was further observed in noncancerous human BEAS-2Blung cells, indicating that this effect is not cancer cell-specific.Mechanistically, in A549 cells, increased total HDAC or decreasedHAT activity could be excluded.